Chronic kidney disease medication found to be ineffective

Researchers compared the use of allopurinol – a commonly used medication to lower blood levels of urate (also known as uric acid) – to a placebo and found it made no difference to the rate of kidney function decline.

A major clinical trial has found that allopurinol does not prevent worsening of kidney disease – despite up to 20 per cent of kidney disease patients being prescribed the medication.

Researchers from UNSW and The George Institute for Global Health collaborated with researchers from the Australasian Kidney Trials Network to conduct a two-year trial – the CKD-FIX Study – across 31 hospitals in Australia and New Zealand and the results were published in the New England Journal of Medicine.