Males of most animal species die earlier than females because their smaller Y chromosome is unable to protect an unhealthy X chromosome, research suggests.
Once genetic lesions for diseases such as cystic fibrosis and haemophilia were identified, the idea of replacing or correcting defective genes grew into what we now call "gene therapy".
Humans, and even pet dogs, are more than just products of genes. As Russell Bonduriansky writes, environments play a vital role in shaping us – even before conception.
An international research team has discovered an important new genetic target for the development of possible treatments for the common inherited blood diseases sickle cell anaemia and thalassaemia.
Microbes may be tiny, but their huge number and diversity mean they can be used to identify environmental impacts early, potentially limiting greater harm to larger organisms, write Katherine Dafforn, Emma Johnston, Inke Falkner and Melanie Sun.
New results confirm we are on the right track to understanding how molecules that coat DNA influence the activity of disease genes, writes Merlin Crossley.
