Professor Colleen Loo

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The largest randomised control trial to evaluate the effectiveness of ketamine as a new treatment for major depression has begun across Australia and New Zealand.

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We should resist pressure to prescribe ketamine to treat depression until clinical trials on the drug's long-term safety and effectiveness are completed, a leading UNSW mental health expert says.

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A drug traditionally used as an anaesthetic and sometimes used recreationally could be effective in preventing suicide in severely depressed patients, says a UNSW academic who has trialled the drug.

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Ketamine is being trialled in people with severe depression and is providing almost instant relief from symptoms, offering fresh hope of a quick new way to manage the illness at its worst.

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Applying mild electrical currents to the brain has been shown to be an effective treatment for depression. But could the treatment also benefit people with bipolar disorder?

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Stimulating the brain with a weak electrical current is a safe and effective treatment for depression and could have other surprise benefits for the body and mind, a major Australian study has found.

A new, non-invasive treatment for depression that delivers barely perceptible electric currents to the scalp has had promising results in a Sydney trial, and researchers are now looking for participants for a follow up study.

UNSW and The Black Dog Institute are seeking participants for a trial of a new, non-invasive form of brain stimulation therapy for depression, known as Direct Current Stimulation (DCS).